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Synthetic pentadecapeptide BPC-157, lyophilized reference standard. Prepared for in vitro laboratory research and chemical analysis.
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Price
$32.92
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Quantity
In Stock · 29 Units Available
- Free FedEx 2-Day shipping over $200. Dispatched the same day when ordered before 4 p.m. PT Monday–Friday, or 11 a.m. PT Saturday. Los Angeles and the surrounding area usually arrive the next business day. Shipping details
- Third-party HPLC tested. Every lot ships with a batch-linked certificate of analysis naming the laboratory, the method and the measured result. Browse certificates
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Certificate of Analysis & Specifications
HPLC Purity
99.87% HPLC
Area Normalization
Assay Content
10.01mg
Quantitative Target
Testing Lab
KMD Analytical
Lot Number
KRSBPC157-10-260814-01
Tested Aug 23, 2026
Storage
36°F to 46°F
Retest Date
Aug 22, 2028
Released COA Library
Published Certificates of Analysis for BPC-157. All released analytical records are preserved here. Pending and in-testing lots are reachable only through the QR printed on the vial.
10mg1 released lot
- View COA
Lot KRSBPC157-10-260814-01
Tested Aug 23, 2026 · KMD Analytical · HPLC 99.87% · Assay 10.01
Related research materials
Customer reviews
Based on 7 reviews
Quality Benchmarks
“The whole purchase was seamless. Accurate inventory, quick confirmation, careful cold shipping, and documentation that matched the shipment exactly. This is how ordering reference materials should work.”
“Tracking updates arrived at every step. Labels were legible and included storage guidance. Exactly what a receiving lab wants to see.”
“Order accuracy was perfect — items and quantities matched what I paid for. The online lot lookup made receiving documentation painless. Nice attention to the small details.”
“The COA link resolved on the first scan. Seals and tamper indicators were intact on arrival. We will order from here again.”
“Order arrived two days ahead of the estimate. The batch page lists purity and retest details we need for our files. A smooth purchasing experience overall.”
“Checkout was straightforward and the confirmation had every detail. Cold packs were still frozen when the box was opened. No complaints from our team.”
“The parcel came well packed with the certificate inside. The certificate of analysis printed on the box matched the online lot record. Consistent with our previous orders from this supplier.”
Research Data
Chemical & Structural Identifiers
- Chemical Name (IUPAC)
- L-glycyl-L-α-glutamyl-L-prolyl-L-prolyl-L-prolylglycyl-L-lysyl-L-prolyl-L-alanyl-L-α-aspartyl-L-α-aspartyl-L-alanylglycyl-L-leucyl-L-valine
- CAS Registry Number
- 137525-51-0
- PubChem CID
- 9941957
- Molecular Formula
- C62H98N16O22
- Molecular Weight
- 1418.70 Da (1419.55 g/mol average)
- Sequence
- H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH (Single-letter: GEPPPGKPADDAGLV)
- SMILES
- CC(C)C[C@@H](C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]3CCCN3C(=O)[C@@H]4CCCN4C(=O)[C@H](CCC(=O)O)NC(=O)CN
- InChIKey
- PCDQPRRSZKQHHS-XBHQNXJUSA-N
- Salt / Counter-Ion
- Supplied as a lyophilized acetate (CH3COO-) or trifluoroacetate (CF3COO-) salt.
- Synonyms
- BPC-157, Pentadecapeptide BPC 157, Body Protection Compound-157, PL 14736, PL-10
Analytical & COA Specifications
- Analytical Purity (RP-HPLC)
- ≥ 99.0% by area normalization under UV detection at λ = 214 nm and 220 nm.
- Identity Confirmation (RP-HPLC RT + UV vs. reference)
- Main peak retention time and UV spectrum conform to the reference standard.
- Physical Characterization
- Dense, white to off-white lyophilized solid cake/powder.
Handling & Stability
Storage. Store dry lyophilized powder desiccated at -20°C to -80°C, protected from moisture and ambient light exposure.
Solubility. Freely soluble in sterile deionized water (≥ 25 mg/mL) and sterile Phosphate-Buffered Saline (PBS, pH 7.4, ≥ 15 mg/mL) for in vitro laboratory assay delivery.
- Handling & Degradation Parameters: Exhibits high structural stability in neutral aqueous solutions; avoid excessive aeration or high-shear vortexing to prevent mechanical denaturation, and aliquot into single-use fractions to eliminate freeze-thaw degradation cycles.
Mechanism & Literature
Structural Origin: Synthetic 15-amino acid peptide derived from a partial sequence isolated from endogenous human gastric juice protein. Engineered as a linear pentadecapeptide with a prominent tri-proline repeating segment (Pro3-Pro4-Pro5) conferring relative resistance to enzymatic hydrolysis in biochemical assay environments.
Cellular Pathways Investigated: Extensively profiled in in vitro cellular models (including human umbilical vein endothelial cells [HUVECs] and tendon-derived fibroblasts) to analyze modulation of the focal adhesion kinase (FAK)-paxillin phosphorylation axis, activation of Early Growth Response-1 (Egr-1), and downstream regulation of vascular endothelial growth factor receptor 2 (VEGFR2) transcription and collagen type I/III synthesis.
References (3)
- Sikiric, P., et al. (1993). A new gastric juice peptide, BPC. An overview of its biochemical characteristics in cellular models. Journal of Physiology (Paris), 87(5), 313–327.
- Chang, C. H., et al. (2011). Pentadecapeptide BPC 157 enhances FAK and paxillin phosphorylation in in-vitro cell migration assays. Biochemical and Biophysical Research Communications, 404(4), 1015–1020.
- Hsieh, P. C., et al. (2017). Biochemical evaluation of BPC-157-induced collagen synthesis and mRNA transcription in tendon fibroblast cultures. Journal of Cellular Physiology, 232(9), 2467–2477.
Technical Laboratory FAQs
What is the sequence origin and primary structure of BPC-157?
BPC-157 is a 15-amino acid synthetic peptide with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, corresponding to a stable fragment derived from gastric juice protein.
Why does BPC-157 exhibit stability in diverse in vitro pH environments?
The peptide's conformation is stabilized by its contiguous tri-proline motif (Pro3-Pro4-Pro5), which creates a rigid polyproline II secondary structure that limits accessibility to non-specific laboratory endopeptidases.
What solvent conditions are standard for preparing in vitro BPC-157 stock assays?
Sterile deionized water or sterile PBS (pH 7.4) provides immediate dissolution at concentrations exceeding 15 mg/mL, providing a neutral carrier solution for cell culture and biochemical modeling.
For Research Use Only. Not for human or animal administration. Not intended to diagnose, treat, cure, or prevent any disease. Sold for laboratory research purposes only.