Two receptor families, one research theme
Growth hormone secretagogues are a research class defined by their receptor targets rather than a single structure. They split into two families: growth hormone-releasing hormone (GHRH) analogs and ghrelin-mimetic / growth hormone secretagogue receptor (GHS-R) agonists.
GHRH analogs act through the GHRH receptor on pituitary cells, while ghrelin mimetics act through GHS-R1a. Both are studied for their downstream signaling in pituitary-cell and receptor-binding models.
GHRH analogs
This family includes modified growth hormone-releasing factor sequences studied for receptor affinity and stability. Examples in the catalog include Tesamorelin and the CJC-1295 series (with and without the drug-affinity-complex modification), which are documented in in vitro receptor-binding and stability assays.
Ghrelin mimetics
Ghrelin mimetics are short synthetic peptides that bind the ghrelin receptor. Catalog examples include GHRP-6 and Ipamorelin. The published literature characterizes them in cell-based assays for receptor activation and downstream intracellular signaling.
What to verify before choosing a material
As with any research peptide, identity, purity, and lot documentation come first. A complete certificate reports the molecular weight by mass spectrometry and purity by HPLC, so the material can be tied to a specific batch and result.